Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63

p53 and p63 are transcription factors -TFs- playing master roles in the DNA-damage response and in the development and maintenance of pluristratified epithelia, respectively. p53 mutations are common in epithelial tumors and HaCaT keratinocytes harbor two p53 alleles -H179Y and R282Q- with gain-of-f...

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Detalles Bibliográficos
Autores principales: Martynova, Elena, Pozzi, Silvia, Basile, Valentina, Dolfini, Diletta, Zambelli, Federico, Imbriano, Carol, Pavesi, Giulio, Mantovani, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326644/
https://www.ncbi.nlm.nih.gov/pubmed/22361592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326644/
https://www.ncbi.nlm.nih.gov/pubmed/22361592

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