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Cytochrome P-450-catalyzed reactive oxygen species production mediates the (–)schisandrin B-induced glutathione and heat shock responses in H9c2 cardiomyocytes

OBJECTIVE: Schisandrin B (Sch B) is the most abundant, active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis (Turcz) Baillon (Schisandraceae). (–)Sch B was found to be the most potent stereoisomer of Sch B in producing cytoprotective action in H9c2 cardiomyocytes. T...

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Detalles Bibliográficos
Autores principales: Chen, Na, Chiu, Po Yee, Leung, Hoi Yan, Ko, Kam Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326913/
https://www.ncbi.nlm.nih.gov/pubmed/22529476
http://dx.doi.org/10.4103/0253-7613.93849