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Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis
The small GTPase RhoA has critical functions in regulating actin dynamics affecting cellular morphogenesis through the RhoA/Rho kinase (ROCK) signaling cascade. RhoA signaling controls stress fiber and focal adhesion formation and cell motility in fibroblasts. RhoA signaling is involved in several a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327311/ https://www.ncbi.nlm.nih.gov/pubmed/22357624 http://dx.doi.org/10.1091/mbc.E11-10-0867 |