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Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis

The small GTPase RhoA has critical functions in regulating actin dynamics affecting cellular morphogenesis through the RhoA/Rho kinase (ROCK) signaling cascade. RhoA signaling controls stress fiber and focal adhesion formation and cell motility in fibroblasts. RhoA signaling is involved in several a...

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Detalles Bibliográficos
Autores principales: Xing, Lei, Yao, Xiaodi, Williams, Kathryn R., Bassell, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327311/
https://www.ncbi.nlm.nih.gov/pubmed/22357624
http://dx.doi.org/10.1091/mbc.E11-10-0867