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Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells

Acid sphingomyelinase (ASM) mediates the formation of membrane raft (MR) redox signalosomes in a process that depends on a local acid microenvironment in coronary arterial endothelial cells (CAECs). However, it is not known how this local acid microenvironment is formed and maintained. The present s...

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Detalles Bibliográficos
Autores principales: Xu, Ming, Xia, Min, Li, Xiao-Xue, Han, Wei-Qing, Boini, Krishna M., Zhang, Fan, Zhang, Yang, Ritter, Joseph K, Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327313/
https://www.ncbi.nlm.nih.gov/pubmed/22357614
http://dx.doi.org/10.1091/mbc.E11-09-0821