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Requirement of translocated lysosomal V1 H(+)-ATPase for activation of membrane acid sphingomyelinase and raft clustering in coronary endothelial cells
Acid sphingomyelinase (ASM) mediates the formation of membrane raft (MR) redox signalosomes in a process that depends on a local acid microenvironment in coronary arterial endothelial cells (CAECs). However, it is not known how this local acid microenvironment is formed and maintained. The present s...
Autores principales: | Xu, Ming, Xia, Min, Li, Xiao-Xue, Han, Wei-Qing, Boini, Krishna M., Zhang, Fan, Zhang, Yang, Ritter, Joseph K, Li, Pin-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327313/ https://www.ncbi.nlm.nih.gov/pubmed/22357614 http://dx.doi.org/10.1091/mbc.E11-09-0821 |
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