Cargando…

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

Mutations in the Bdnf gene, which produces transcripts with either short or long 3′ untranslated regions (3′UTRs), cause human obesity; however, the precise role of BDNF in the regulation of energy balance remains unknown. Here we show the relationship between long 3′UTR Bdnf mRNA, leptin, neuronal...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Guey-Ying, An, Juan Ji, Gharami, Kusumika, Waterhouse, Emily G., Vanevski, Filip, Jones, Kevin R., Xu, Baoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327556/
https://www.ncbi.nlm.nih.gov/pubmed/22426422
http://dx.doi.org/10.1038/nm.2687