Cargando…

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

Mutations in the Bdnf gene, which produces transcripts with either short or long 3′ untranslated regions (3′UTRs), cause human obesity; however, the precise role of BDNF in the regulation of energy balance remains unknown. Here we show the relationship between long 3′UTR Bdnf mRNA, leptin, neuronal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Guey-Ying, An, Juan Ji, Gharami, Kusumika, Waterhouse, Emily G., Vanevski, Filip, Jones, Kevin R., Xu, Baoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327556/ https://www.ncbi.nlm.nih.gov/pubmed/22426422 http://dx.doi.org/10.1038/nm.2687

Ejemplares similares

HuD Interacts with Bdnf mRNA and Is Essential for Activity-Induced BDNF Synthesis in Dendrites
por: Vanevski, Filip, et al.
Publicado: (2015)

Molecular and neural bases underlying roles of BDNF in the control of body weight
por: Vanevski, Filip, et al.
Publicado: (2013)

Rapid and Lasting Effects of Activating BDNF-Expressing PVH Neurons on Energy Balance
por: Wu, Shaw-wen, et al.
Publicado: (2022)

The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF
por: Scabia, Gaia, et al.
Publicado: (2018)

BDNF signaling and survival of striatal neurons
por: Baydyuk, Maryna, et al.
Publicado: (2014)

Dendritic targeting of short and long 3′ UTR BDNF mRNA is regulated by BDNF or NT-3 and distinct sets of RNA-binding proteins
por: Vicario, Annalisa, et al.
Publicado: (2015)

Roles of leptin on energy balance and thermoregulation in Eothenomys miletus
por: Chen, Huibao, et al.
Publicado: (2022)

Distinct role of 5′UTR sequences in dendritic trafficking of BDNF mRNA: additional mechanisms for the BDNF splice variants spatial code
por: Colliva, Andrea, et al.
Publicado: (2021)

Preoptic leptin signaling modulates energy balance independent of body temperature regulation
por: Yu, Sangho, et al.
Publicado: (2018)

Ventromedial hypothalamic expression of Bdnf is required to establish normal patterns of afferent GABAergic connectivity and responses to hypoglycemia
por: Kamitakahara, Anna, et al.
Publicado: (2015)

Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance
por: Rupp, Alan C., et al.
Publicado: (2018)

The Role of BDNF, Leptin, and Catecholamines in Reward Learning in Bulimia Nervosa
por: Homan, Philipp, et al.
Publicado: (2015)

Beyond Leptin: Emerging Candidates for the Integration of Metabolic and Reproductive Function during Negative Energy Balance
por: True, Cadence, et al.
Publicado: (2011)

Rho-kinase Regulates Energy Balance by Targeting Hypothalamic Leptin Receptor Signaling
por: Huang, Hu, et al.
Publicado: (2012)

Edaravone alleviated propofol‐induced neural injury in developing rats by BDNF/TrkB pathway
por: Yang, Yangliang, et al.
Publicado: (2021)

BDNF signaling during the lifetime of dendritic spines
por: Zagrebelsky, Marta, et al.
Publicado: (2020)

Leptin-inhibited PBN neurons enhance counter-regulatory responses to hypoglycemia in negative energy balance
por: Flak, Jonathan N., et al.
Publicado: (2014)

Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system
por: Khanh, Doan V., et al.
Publicado: (2014)

Dorsal vagal complex and hypothalamic glia differentially respond to leptin and energy balance dysregulation
por: Stein, Lauren M., et al.
Publicado: (2020)

Impacts of essential amino acids on energy balance
por: Xiao, Fei, et al.
Publicado: (2021)

Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway
por: Yang, Yangliang, et al.
Publicado: (2021)

Glucocorticoid affects dendritic transport of BDNF-containing vesicles
por: Adachi, Naoki, et al.
Publicado: (2015)

Leptin action via hypothalamic nitric oxide synthase-1 neurons controls energy balance
por: Leshan, Rebecca L., et al.
Publicado: (2012)

Altered function of arcuate leptin receptor expressing neuropeptide Y neurons depending on energy balance
por: Lee, Nicola J., et al.
Publicado: (2023)

The 14th Ile residue is essential for Leptin function in regulating energy homeostasis in rat
por: Xu, Shuyang, et al.
Publicado: (2016)

Fingolimod Modulates Dendritic Architecture in a BDNF-Dependent Manner
por: Patnaik, Abhisarika, et al.
Publicado: (2020)

Effect of Different Levels of Energy Diet Restriction on Energy Balance, Leptin and CL Development, Vascularization, and Function in South American Camelids
por: Norambuena, Cecilia, et al.
Publicado: (2020)

TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
por: An, Juan Ji, et al.
Publicado: (2020)

Balance between BDNF and Semaphorins gates the innervation of the mammary gland
por: Sar Shalom, Hadas, et al.
Publicado: (2019)

Distinct cellular toxicity of two mutant huntingtin mRNA variants due to translation regulation
por: Xu, Haifei, et al.
Publicado: (2017)

Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons
por: Cheung, Zelda H, et al.
Publicado: (2007)

Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF
por: Choi, Se Hoon, et al.
Publicado: (2009)

BDNF pro-peptide regulates dendritic spines via caspase-3
por: Guo, J, et al.
Publicado: (2016)

Leptin promotes rapid dynamic changes in hippocampal dendritic morphology
por: O’Malley, Dervla, et al.
Publicado: (2007)

The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates
por: Park, Soyoung, et al.
Publicado: (2020)

Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis
por: Barrios, Vicente, et al.
Publicado: (2021)

Leptin Increases: Physiological Roles in the Control of Sympathetic Nerve Activity, Energy Balance, and the Hypothalamic–Pituitary–Thyroid Axis
por: Martelli, Davide, et al.
Publicado: (2023)

Relationship of Glucose, C-peptide, Leptin, and BDNF in Maternal and Umbilical Vein Blood in Type-1 Diabetes
por: Delmis, Josip, et al.
Publicado: (2023)

Measurement of the levels of leptin, BDNF associated with polymorphisms LEP G2548A, LEPR Gln223Arg and BDNF Val66Met in Thai with metabolic syndrome
por: Suriyaprom, Kanjana, et al.
Publicado: (2014)

Serum leptin concentrations, leptin mRNA expression, and food intake during the estrous cycle in rats
por: Fungfuang, Wirasak, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_nrt0scki63m43vmksrljc31abe