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Association of Combined p73 and p53 Genetic Variants with Tumor HPV16-Positive Oropharyngeal Cancer

p53 and p73 interact with human papillomavirus (HPV) E6 and E7 oncoproteins. The interplay between p53 and p73 and HPV16 may lead to deregulation of cell cycle and apoptosis, through which inflammation/immune responses control the HPV clearance and escape of immune surveillance, and subsequently con...

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Detalles Bibliográficos
Autores principales: Wang, Zhongqiu, Sturgis, Erich M., Guo, Wei, Song, Xicheng, Zhang, Fenghua, Xu, Li, Wei, Qingyi, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327667/
https://www.ncbi.nlm.nih.gov/pubmed/22523600
http://dx.doi.org/10.1371/journal.pone.0035522