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Proteins from Avastin® (bevacizumab) Show Tyrosine Nitrations for which the Consequences Are Completely Unclear

Avastin® (bevacizumab) is a protein drug widely used for cancer treatment although its further use is questionable due to serious side effects reported. As no systematic proteomic study on posttranslational modifications (PTMs) was reported so far, it was the aim of the current study to use a gel-ba...

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Detalles Bibliográficos
Autores principales: Wan, Jia, Csaszar, Edina, Chen, Wei-Qiang, Li, Kongzhao, Lubec, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327692/
https://www.ncbi.nlm.nih.gov/pubmed/22523550
http://dx.doi.org/10.1371/journal.pone.0034511