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Ablation of Proliferating Cells in the CNS Exacerbates Motor Neuron Disease Caused by Mutant Superoxide Dismutase

Proliferation of glia and immune cells is a common pathological feature of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Here, to investigate the role of proliferating cells in motor neuron disease, SOD1(G93A) transgenic mice were treated intracerebroventicularly (IC...

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Detalles Bibliográficos
Autores principales: Audet, Jean-Nicolas, Gowing, Geneviève, Paradis, Renée, Soucy, Geneviève, Julien, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327706/
https://www.ncbi.nlm.nih.gov/pubmed/22523565
http://dx.doi.org/10.1371/journal.pone.0034932