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Ablation of Proliferating Cells in the CNS Exacerbates Motor Neuron Disease Caused by Mutant Superoxide Dismutase
Proliferation of glia and immune cells is a common pathological feature of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Here, to investigate the role of proliferating cells in motor neuron disease, SOD1(G93A) transgenic mice were treated intracerebroventicularly (IC...
Autores principales: | Audet, Jean-Nicolas, Gowing, Geneviève, Paradis, Renée, Soucy, Geneviève, Julien, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327706/ https://www.ncbi.nlm.nih.gov/pubmed/22523565 http://dx.doi.org/10.1371/journal.pone.0034932 |
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