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Glutaredoxin-1 Overexpression Enhances Neovascularization and Diminishes Ventricular Remodeling in Chronic Myocardial Infarction

Oxidative stress plays a critical role in the pathophysiology of cardiac failure, including the modulation of neovascularization following myocardial infarction (MI). Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively maintain intracellular thiol-redox homeostasis by sca...

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Detalles Bibliográficos
Autores principales: Adluri, Ram Sudheer, Thirunavukkarasu, Mahesh, Zhan, Lijun, Dunna, Nageswara Rao, Akita, Yuzo, Selvaraju, Vaithinathan, Otani, Hajime, Sanchez, Juan A., Ho, Ye-Shih, Maulik, Nilanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327713/
https://www.ncbi.nlm.nih.gov/pubmed/22523530
http://dx.doi.org/10.1371/journal.pone.0034790