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Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation

RNAa (RNA activation) is a mechanism by which small dsRNA (double-stranded RNA), termed saRNA (small activating RNA), target promoter sequences to induce gene expression. This technique represents a novel approach to gene overexpression without the use of exogenous DNA. In the present study, we inve...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoling, Wang, Ji, Huang, Vera, Place, Robert F., Li, Long-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327998/
https://www.ncbi.nlm.nih.gov/pubmed/22339500
http://dx.doi.org/10.1042/BJ20111491