Calcineurin Controls Voltage-Dependent-Inactivation (VDI) of the Normal and Timothy Cardiac Channels

Ca(2+)-entry in the heart is tightly controlled by Cav1.2 inactivation, which involves Ca(2+)-dependent inactivation (CDI) and voltage-dependent inactivation (VDI) components. Timothy syndrome, a subtype-form of congenital long-QT syndrome, results from a nearly complete elimination of VDI by the G4...

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Detalles Bibliográficos
Autores principales: Cohen-Kutner, Moshe, Yahalom, Yfat, Trus, Michael, Atlas, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328044/
https://www.ncbi.nlm.nih.gov/pubmed/22511998
http://dx.doi.org/10.1038/srep00366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328044/
https://www.ncbi.nlm.nih.gov/pubmed/22511998
http://dx.doi.org/10.1038/srep00366

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