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Radical-Mediated Enzymatic Methylation: A Tale of Two SAMS

[Image: see text] Methylation is an essential and ubiquitous reaction that plays an important role in a wide range of biological processes. Most biological methylations use S-adenosylmethionine (SAM) as the methyl donor and proceed via an S(N)2 displacement mechanism. However, researchers have disco...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, van der Donk, Wilfred A., Liu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328197/
https://www.ncbi.nlm.nih.gov/pubmed/22097883
http://dx.doi.org/10.1021/ar200202c