Essential role of EBF1 in the generation and function of distinct mature B cell types

The transcription factor EBF1 is essential for lineage specification in early B cell development. In this study, we demonstrate by conditional mutagenesis that EBF1 is required for B cell commitment, pro–B cell development, and subsequent transition to the pre–B cell stage. Later in B cell developme...

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Detalles Bibliográficos
Autores principales: Vilagos, Bojan, Hoffmann, Mareike, Souabni, Abdallah, Sun, Qiong, Werner, Barbara, Medvedovic, Jasna, Bilic, Ivan, Minnich, Martina, Axelsson, Elin, Jaritz, Markus, Busslinger, Meinrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328360/
https://www.ncbi.nlm.nih.gov/pubmed/22473956
http://dx.doi.org/10.1084/jem.20112422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328360/
https://www.ncbi.nlm.nih.gov/pubmed/22473956
http://dx.doi.org/10.1084/jem.20112422

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