ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-loaded macrophages in the arterial wall. We demonstrate that macrophage lipid body formation can be induced by modified lipoproteins or by inflammatory Toll-like receptor agonists. We used an unbiased approa...

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Detalles Bibliográficos
Autores principales: Gold, Elizabeth S., Ramsey, Stephen A., Sartain, Mark J., Selinummi, Jyrki, Podolsky, Irina, Rodriguez, David J., Moritz, Robert L., Aderem, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328364/
https://www.ncbi.nlm.nih.gov/pubmed/22473958
http://dx.doi.org/10.1084/jem.20111202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328364/
https://www.ncbi.nlm.nih.gov/pubmed/22473958
http://dx.doi.org/10.1084/jem.20111202

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