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ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-loaded macrophages in the arterial wall. We demonstrate that macrophage lipid body formation can be induced by modified lipoproteins or by inflammatory Toll-like receptor agonists. We used an unbiased approa...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328364/ https://www.ncbi.nlm.nih.gov/pubmed/22473958 http://dx.doi.org/10.1084/jem.20111202 |