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Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

Deep vein thrombosis (DVT) is a major cause of cardiovascular death. The sequence of events that promote DVT remains obscure, largely as a result of the lack of an appropriate rodent model. We describe a novel mouse model of DVT which reproduces a frequent trigger and resembles the time course, hist...

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Detalles Bibliográficos
Autores principales: von Brühl, Marie-Luise, Stark, Konstantin, Steinhart, Alexander, Chandraratne, Sue, Konrad, Ildiko, Lorenz, Michael, Khandoga, Alexander, Tirniceriu, Anca, Coletti, Raffaele, Köllnberger, Maria, Byrne, Robert A., Laitinen, Iina, Walch, Axel, Brill, Alexander, Pfeiler, Susanne, Manukyan, Davit, Braun, Siegmund, Lange, Philipp, Riegger, Julia, Ware, Jerry, Eckart, Annekathrin, Haidari, Selgai, Rudelius, Martina, Schulz, Christian, Echtler, Katrin, Brinkmann, Volker, Schwaiger, Markus, Preissner, Klaus T., Wagner, Denisa D., Mackman, Nigel, Engelmann, Bernd, Massberg, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328366/
https://www.ncbi.nlm.nih.gov/pubmed/22451716
http://dx.doi.org/10.1084/jem.20112322