The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

The Mst1 kinase is an important regulator of murine T cell adhesion, migration, proliferation, and apoptosis. In this study, we analyze mice lacking both Mst1 and Mst2 in hematopoietic cells. Compared with wild-type mice, these double knockout (DKO) mice exhibit a severe reduction in the number of m...

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Detalles Bibliográficos
Autores principales: Mou, Fan, Praskova, Maria, Xia, Fan, Van Buren, Denille, Hock, Hanno, Avruch, Joseph, Zhou, Dawang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328371/
https://www.ncbi.nlm.nih.gov/pubmed/22412158
http://dx.doi.org/10.1084/jem.20111692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328371/
https://www.ncbi.nlm.nih.gov/pubmed/22412158
http://dx.doi.org/10.1084/jem.20111692

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