Cargando…
The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes
The Mst1 kinase is an important regulator of murine T cell adhesion, migration, proliferation, and apoptosis. In this study, we analyze mice lacking both Mst1 and Mst2 in hematopoietic cells. Compared with wild-type mice, these double knockout (DKO) mice exhibit a severe reduction in the number of m...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328371/ https://www.ncbi.nlm.nih.gov/pubmed/22412158 http://dx.doi.org/10.1084/jem.20111692 |