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DDB2 promotes chromatin decondensation at UV-induced DNA damage

Nucleotide excision repair (NER) is the principal pathway that removes helix-distorting deoxyribonucleic acid (DNA) damage from the mammalian genome. Recognition of DNA lesions by xeroderma pigmentosum group C (XPC) protein in chromatin is stimulated by the damaged DNA-binding protein 2 (DDB2), whic...

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Detalles Bibliográficos
Autores principales: Luijsterburg, Martijn S., Lindh, Michael, Acs, Klara, Vrouwe, Mischa G., Pines, Alex, van Attikum, Haico, Mullenders, Leon H., Dantuma, Nico P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328393/
https://www.ncbi.nlm.nih.gov/pubmed/22492724
http://dx.doi.org/10.1083/jcb.201106074