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Synergistic Interactions between the NS3(hel) and E Proteins Contribute to the Virulence of Dengue Virus Type 1
BACKGROUND: Dengue includes a broad range of symptoms, ranging from fever to hemorrhagic fever and may occasionally have alternative clinical presentations. Many possible viral genetic determinants of the intrinsic virulence of dengue virus (DENV) in the host have been identified, but no conclusive...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328427/ https://www.ncbi.nlm.nih.gov/pubmed/22530074 http://dx.doi.org/10.1371/journal.pntd.0001624 |