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Synergistic Interactions between the NS3(hel) and E Proteins Contribute to the Virulence of Dengue Virus Type 1

BACKGROUND: Dengue includes a broad range of symptoms, ranging from fever to hemorrhagic fever and may occasionally have alternative clinical presentations. Many possible viral genetic determinants of the intrinsic virulence of dengue virus (DENV) in the host have been identified, but no conclusive...

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Detalles Bibliográficos
Autores principales: de Borba, Luana, Strottmann, Daisy M., de Noronha, Lucia, Mason, Peter W., Duarte dos Santos, Claudia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328427/
https://www.ncbi.nlm.nih.gov/pubmed/22530074
http://dx.doi.org/10.1371/journal.pntd.0001624