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Polysaccharide Specific Monoclonal Antibodies Provide Passive Protection against Intranasal Challenge with Burkholderia pseudomallei

Burkholderia pseudomallei is a Gram-negative bacillus that is the causative agent of melioidosis. The bacterium is inherently resistant to many antibiotics and mortality rates remain high in endemic areas. The lipopolysaccharide (LPS) and capsular polysaccharide (CPS) are two surface-associated anti...

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Detalles Bibliográficos
Autores principales: AuCoin, David P., Reed, Dana E., Marlenee, Nicole L., Bowen, Richard A., Thorkildson, Peter, Judy, Barbara M., Torres, Alfredo G., Kozel, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328442/
https://www.ncbi.nlm.nih.gov/pubmed/22530013
http://dx.doi.org/10.1371/journal.pone.0035386