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Exogenous Amino Acids Are Essential for Interleukin-7 Induced CD8 T Cell Gowth

IL-7 signalling is important in regulating both survival and cellular size (growth) of T cells. While glucose metabolism has previously been implicated in the mechanism of IL-7 induced survival and growth, the role of amino acids has not before been reported. Here, we show IL-7 dependent T cell surv...

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Detalles Bibliográficos
Autores principales: Pearson, Claire, Silva, Ana, Seddon, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328464/
https://www.ncbi.nlm.nih.gov/pubmed/22529903
http://dx.doi.org/10.1371/journal.pone.0033998