Selenocysteine Insertion Sequence Binding Protein 2L Is Implicated as a Novel Post-Transcriptional Regulator of Selenoprotein Expression

The amino acid selenocysteine (Sec) is encoded by UGA codons. Recoding of UGA from stop to Sec requires a Sec insertion sequence (SECIS) element in the 3′ UTR of selenoprotein mRNAs. SECIS binding protein 2 (SBP2) binds the SECIS element and is essential for Sec incorporation into the nascent peptid...

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Detalles Bibliográficos
Autores principales: Donovan, Jesse, Copeland, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328465/
https://www.ncbi.nlm.nih.gov/pubmed/22530054
http://dx.doi.org/10.1371/journal.pone.0035581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328465/
https://www.ncbi.nlm.nih.gov/pubmed/22530054
http://dx.doi.org/10.1371/journal.pone.0035581

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