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Vaccine Efficacy against Malaria by the Combination of Porcine Parvovirus-Like Particles and Vaccinia Virus Vectors Expressing CS of Plasmodium

With the aim to develop an efficient and cost-effective approach to control malaria, we have generated porcine parvovirus-like particles (PPV-VLPs) carrying the CD8(+) T cell epitope (SYVPSAEQI) of the circumsporozoite (CS) protein from Plasmodium yoelii fused to the PPV VP2 capsid protein (PPV-PYCS...

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Detalles Bibliográficos
Autores principales: Rodríguez, Dolores, González-Aseguinolaza, Gloria, Rodríguez, Juan R., Vijayan, Aneesh, Gherardi, Magdalena, Rueda, Paloma, Casal, J. Ignacio, Esteban, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328484/
https://www.ncbi.nlm.nih.gov/pubmed/22529915
http://dx.doi.org/10.1371/journal.pone.0034445