Designing and Analyzing Clinical Trials with Composite Outcomes: Consideration of Possible Treatment Differences between the Individual Outcomes

When the individual outcomes within a composite outcome appear to have different treatment effects, either in magnitude or direction, researchers may question the validity or appropriateness of using this composite outcome as a basis for measuring overall treatment effect in a randomized controlled...

Descripción completa

Detalles Bibliográficos
Autores principales: Pogue, Janice, Devereaux, P. J., Thabane, Lehana, Yusuf, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328496/
https://www.ncbi.nlm.nih.gov/pubmed/22529934
http://dx.doi.org/10.1371/journal.pone.0034785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328496/
https://www.ncbi.nlm.nih.gov/pubmed/22529934
http://dx.doi.org/10.1371/journal.pone.0034785

Ejemplares similares