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Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms

Infection with Neisseria gonorrhoeae does not induce specific immunity or immune memory. Our previous studies in a murine model of vaginal gonococcal infection showed that innate immunity governed by Th17 cells was a critical aspect of the immune response elicited by this pathogen. Herein we show th...

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Detalles Bibliográficos
Autores principales: Liu, Yingru, Islam, Epshita A., Jarvis, Gary A., Gray-Owen, Scott D., Russell, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328619/
https://www.ncbi.nlm.nih.gov/pubmed/22354319
http://dx.doi.org/10.1038/mi.2012.12