Cargando…
Neisseria gonorrhoeae selectively suppresses the development of Th1 and Th2 cells, and enhances Th17 cell responses, through TGF-β-dependent mechanisms
Infection with Neisseria gonorrhoeae does not induce specific immunity or immune memory. Our previous studies in a murine model of vaginal gonococcal infection showed that innate immunity governed by Th17 cells was a critical aspect of the immune response elicited by this pathogen. Herein we show th...
Autores principales: | Liu, Yingru, Islam, Epshita A., Jarvis, Gary A., Gray-Owen, Scott D., Russell, Michael W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328619/ https://www.ncbi.nlm.nih.gov/pubmed/22354319 http://dx.doi.org/10.1038/mi.2012.12 |
Ejemplares similares
-
Diversion of the Immune Response to Neisseria gonorrhoeae from Th17 to Th1/Th2 by Treatment with Anti-Transforming Growth Factor β Antibody Generates Immunological Memory and Protective Immunity
por: Liu, Yingru, et al.
Publicado: (2011) -
Critical role of Th17 responses in a murine model of Neisseria gonorrhoeae genital infection
por: Feinen, Brandon, et al.
Publicado: (2010) -
Experimental Vaccine Induces Th1-driven Immune Responses and Resistance to Neisseria gonorrhoeae Infection in a Murine Model
por: Liu, Yingru, et al.
Publicado: (2017) -
TRIMming TGF-β signals in Th17 cells
por: Rapaport, Aaron S., et al.
Publicado: (2018) -
Suppression of host adaptive immune responses by Neisseria gonorrhoeae: role of interleukin 10 and type 1 regulatory T cells
por: Liu, Yingru, et al.
Publicado: (2013)