T Cell-Biased Immune Responses Generated by a Mucosally-targeted Adenovirus-Sigma 1 Vaccine

INTRODUCTION: Since, most pathogens enter through the mucosa it is important to develop vaccines that induce mucosal immunity. To this end, we generated a novel adenovirus (Ad) vaccine that displays the sigma1 protein from reovirus to target junctional adhesion molecule 1 (JAM1) and sialic acid. MAT...

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Detalles Bibliográficos
Autores principales: Weaver, Eric A., Mercier, George T., Gottschalk, Stephen, Barry, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328625/
https://www.ncbi.nlm.nih.gov/pubmed/22377931
http://dx.doi.org/10.1038/mi.2012.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328625/
https://www.ncbi.nlm.nih.gov/pubmed/22377931
http://dx.doi.org/10.1038/mi.2012.11

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