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T Cell-Biased Immune Responses Generated by a Mucosally-targeted Adenovirus-Sigma 1 Vaccine
INTRODUCTION: Since, most pathogens enter through the mucosa it is important to develop vaccines that induce mucosal immunity. To this end, we generated a novel adenovirus (Ad) vaccine that displays the sigma1 protein from reovirus to target junctional adhesion molecule 1 (JAM1) and sialic acid. MAT...
Autores principales: | Weaver, Eric A., Mercier, George T., Gottschalk, Stephen, Barry, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328625/ https://www.ncbi.nlm.nih.gov/pubmed/22377931 http://dx.doi.org/10.1038/mi.2012.11 |
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