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T Cell-Biased Immune Responses Generated by a Mucosally-targeted Adenovirus-Sigma 1 Vaccine

INTRODUCTION: Since, most pathogens enter through the mucosa it is important to develop vaccines that induce mucosal immunity. To this end, we generated a novel adenovirus (Ad) vaccine that displays the sigma1 protein from reovirus to target junctional adhesion molecule 1 (JAM1) and sialic acid. MAT...

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Detalles Bibliográficos
Autores principales:	Weaver, Eric A., Mercier, George T., Gottschalk, Stephen, Barry, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328625/ https://www.ncbi.nlm.nih.gov/pubmed/22377931 http://dx.doi.org/10.1038/mi.2012.11

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