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Evidence of early involvement of apoptosis inducing factor-induced neuronal death in Alzheimer brain

Apoptosis inducing factor (AIF) has been proposed to act as a putative reactive oxygen species scavenger in mitochondria. When apoptotic cell death is triggered, AIF translocates to the nucleus, where it leads to nuclear chromatin condensation and large-scale DNA fragmentation which result in caspas...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Hye, Cheon, Young-Hee, Woo, Ran-Sook, Song, Dae-Yong, Moon, Cheil, Baik, Tai-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328738/
https://www.ncbi.nlm.nih.gov/pubmed/22536549
http://dx.doi.org/10.5115/acb.2012.45.1.26