Dyskeratosis congenita and the DNA damage response

Dyskeratosis congenita (DC) is a heterogeneous bone marrow failure disorder with known mutations in components of telomerase and telomere shelterin. Recent work in a mouse model with a dyskerin mutation has implicated an increased DNA damage response as part of the cellular pathology, while mouse mo...

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Detalles Bibliográficos
Autores principales: Kirwan, Michael, Beswick, Richard, Walne, Amanda J, Hossain, Upal, Casimir, Colin, Vulliamy, Tom, Dokal, Inderjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Paediatric
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328754/
https://www.ncbi.nlm.nih.gov/pubmed/21477209
http://dx.doi.org/10.1111/j.1365-2141.2011.08679.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328754/
https://www.ncbi.nlm.nih.gov/pubmed/21477209
http://dx.doi.org/10.1111/j.1365-2141.2011.08679.x

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