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Genotype-phenotype correlation in multiple endocrine neoplasia type 2
Multiple endocrine neoplasia type 2 is an autosomal-dominant hereditary cancer syndrome caused by missense gain-of-function mutations of the rearranged during transfection proto-oncogene, which encodes the receptor tyrosine kinase, on chromosome 10. It has a strong penetrance of medullary thyroid ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328821/ https://www.ncbi.nlm.nih.gov/pubmed/22584709 http://dx.doi.org/10.6061/clinics/2012(Sup01)13 |