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Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2

Multiple endocrine neoplasia type 2 is an inherited cancer syndrome characterized by tumors of thyroid and adrenal tissues. Germline mutations of the REarranged during Transfection (RET) proto-oncogene, leading to its unregulated activation, are the underlying cause of this disease. Multiple endocri...

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Detalles Bibliográficos
Autores principales: Wagner, Simona M., Zhu, ShuJun, Nicolescu, Adrian C., Mulligan, Lois M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328826/
https://www.ncbi.nlm.nih.gov/pubmed/22584710
http://dx.doi.org/10.6061/clinics/2012(Sup01)14