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Poliovirus trafficking toward central nervous system via human poliovirus receptor-dependent and -independent pathway

In humans, paralytic poliomyelitis results from the invasion of the central nervous system (CNS) by circulating poliovirus (PV) via the blood–brain barrier (BBB). After the virus enters the CNS, it replicates in neurons, especially in motor neurons, inducing the cell death that causes paralytic poli...

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Detalles Bibliográficos
Autores principales: Ohka, Seii, Nihei, Coh-ichi, Yamazaki, Manabu, Nomoto, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328850/
https://www.ncbi.nlm.nih.gov/pubmed/22529845
http://dx.doi.org/10.3389/fmicb.2012.00147