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Amelioration of Glucolipotoxicity-Induced Endoplasmic Reticulum Stress by a “Chemical Chaperone” in Human THP-1 Monocytes

Chronic ER stress is emerging as a trigger that imbalances a number of systemic and arterial-wall factors and promote atherosclerosis. Macrophage apoptosis within advanced atherosclerotic lesions is also known to increase the risk of atherothrombotic disease. We hypothesize that glucolipotoxicity mi...

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Detalles Bibliográficos
Autores principales: Lenin, Raji, Maria, Mariawilliam Sneha, Agrawal, Madhur, Balasubramanyam, Jayashree, Mohan, Viswanathan, Balasubramanyam, Muthuswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328920/
https://www.ncbi.nlm.nih.gov/pubmed/22550476
http://dx.doi.org/10.1155/2012/356487