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Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival

Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. These selective forms of autophagy, inclu...

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Detalles Bibliográficos
Autores principales: Hughson, Luke R. K., Poon, Vincent I., Spowart, Jaeline E., Lum, Julian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328951/
https://www.ncbi.nlm.nih.gov/pubmed/22550492
http://dx.doi.org/10.1155/2012/872091