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Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. These selective forms of autophagy, inclu...
Autores principales: | Hughson, Luke R. K., Poon, Vincent I., Spowart, Jaeline E., Lum, Julian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328951/ https://www.ncbi.nlm.nih.gov/pubmed/22550492 http://dx.doi.org/10.1155/2012/872091 |
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