Allosteric Activation of the Phosphoinositide Phosphatase Sac1 by Anionic Phospholipids

[Image: see text] Sac family phosphoinositide phosphatases comprise an evolutionarily conserved family of enzymes in eukaryotes. Our recently determined crystal structure of the Sac phosphatase domain of yeast Sac1, the founding member of the Sac family proteins, revealed a unique conformation of th...

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Detalles Bibliográficos
Autores principales: Zhong, Shurong, Hsu, FoSheng, Stefan, Christopher J., Wu, Xiaochun, Patel, Anamika, Cosgrove, Michael S., Mao, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329130/
https://www.ncbi.nlm.nih.gov/pubmed/22452743
http://dx.doi.org/10.1021/bi300086c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329130/
https://www.ncbi.nlm.nih.gov/pubmed/22452743
http://dx.doi.org/10.1021/bi300086c

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