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HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro

HSV-1 infection in the cornea could lead to blindness. The infected cell polypeptide 4 (ICP4) of herpes simplex virus 1 (HSV-1) is a regulator of viral transcription that is required for productive infection. It has been previously demonstrated that miR-H6 encoded from HSV-1 genome targets ICP4 to h...

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Detalles Bibliográficos
Autores principales: Duan, Fang, Liao, Jingyu, Huang, Qiang, Nie, Yuhong, Wu, Kaili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329371/
https://www.ncbi.nlm.nih.gov/pubmed/22550533
http://dx.doi.org/10.1155/2012/192791