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Nuclear Reprogramming: Kinetics of Cell Cycle and Metabolic Progression as Determinants of Success
Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage. Inadequate adaptation of the somatic nucleus to the embryonic cell cy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329427/ https://www.ncbi.nlm.nih.gov/pubmed/22530006 http://dx.doi.org/10.1371/journal.pone.0035322 |