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Propylthiouracil Is Teratogenic in Murine Embryos

BACKGROUND: Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD) propylthiouracil (PTU) and methimazole (MMI). PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects ha...

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Detalles Bibliográficos
Autores principales: Benavides, Valeria C., Mallela, Murali K., Booth, Carmen J., Wendler, Christopher C., Rivkees, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329451/
https://www.ncbi.nlm.nih.gov/pubmed/22529993
http://dx.doi.org/10.1371/journal.pone.0035213