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Comparison of methods for calculating conditional expectations of sufficient statistics for continuous time Markov chains

BACKGROUND: Continuous time Markov chains (CTMCs) is a widely used model for describing the evolution of DNA sequences on the nucleotide, amino acid or codon level. The sufficient statistics for CTMCs are the time spent in a state and the number of changes between any two states. In applications pas...

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Detalles Bibliográficos
Autores principales: Tataru, Paula, Hobolth, Asger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329461/
https://www.ncbi.nlm.nih.gov/pubmed/22142146
http://dx.doi.org/10.1186/1471-2105-12-465