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Comparison of methods for calculating conditional expectations of sufficient statistics for continuous time Markov chains
BACKGROUND: Continuous time Markov chains (CTMCs) is a widely used model for describing the evolution of DNA sequences on the nucleotide, amino acid or codon level. The sufficient statistics for CTMCs are the time spent in a state and the number of changes between any two states. In applications pas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329461/ https://www.ncbi.nlm.nih.gov/pubmed/22142146 http://dx.doi.org/10.1186/1471-2105-12-465 |