Overcoming Multidrug Resistance via Photodestruction of ABCG2-Rich Extracellular Vesicles Sequestering Photosensitive Chemotherapeutics

Multidrug resistance (MDR) remains a dominant impediment to curative cancer chemotherapy. Efflux transporters of the ATP-binding cassette (ABC) superfamily including ABCG2, ABCB1 and ABCC1 mediate MDR to multiple structurally and functionally distinct antitumor agents. Recently we identified a novel...

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Detalles Bibliográficos
Autores principales: Goler-Baron, Vicky, Assaraf, Yehuda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329466/
https://www.ncbi.nlm.nih.gov/pubmed/22530032
http://dx.doi.org/10.1371/journal.pone.0035487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329466/
https://www.ncbi.nlm.nih.gov/pubmed/22530032
http://dx.doi.org/10.1371/journal.pone.0035487

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