Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics

Chirality is an interesting topic and it is meaningful to explore the interactions between chiral small molecules and stereoselective biomacromolecules, with pre-clinical and clinical significances. We have previously demonstrated that 20(S)-ginsenoside Rh2 is an effective P-glycoprotein (P-gp) inhi...

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Detalles Bibliográficos
Autores principales: Zhang, Jingwei, Zhou, Fang, Niu, Fang, Lu, Meng, Wu, Xiaolan, Sun, Jianguo, Wang, Guangji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329467/
https://www.ncbi.nlm.nih.gov/pubmed/22530069
http://dx.doi.org/10.1371/journal.pone.0035768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329467/
https://www.ncbi.nlm.nih.gov/pubmed/22530069
http://dx.doi.org/10.1371/journal.pone.0035768

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