A Novel Dual-Color Reporter for Identifying Insulin-Producing Beta- Cells and Classifying Heterogeneity of Insulinoma Cell Lines

Many research studies use immortalized cell lines as surrogates for primary beta- cells. We describe the production and use of a novel “indirect" dual-fluorescent reporter system that leads to mutually exclusive expression of EGFP in insulin-producing (INS(+)) beta-cells or mCherry in non-beta-...

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Detalles Bibliográficos
Autores principales: Lee, Nan Sook, Rohan, Joyce G., Zitting, Madison, Kamath, Sonia, Weitz, Andrew, Sipos, Arnold, Salvaterra, Paul M., Hasegawa, Kouichi, Pera, Martin, Chow, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329476/
https://www.ncbi.nlm.nih.gov/pubmed/22530041
http://dx.doi.org/10.1371/journal.pone.0035521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329476/
https://www.ncbi.nlm.nih.gov/pubmed/22530041
http://dx.doi.org/10.1371/journal.pone.0035521

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