Staphylococcal Panton-Valentine Leukocidin Induces Pro-Inflammatory Cytokine Production and Nuclear Factor-Kappa B Activation in Neutrophils

Panton-Valentine leukocidin (PVL) is a cytotoxin secreted by Staphylococcus aureus and associated with severe necrotizing infections. PVL targets polymorphonuclear leukocytes, especially neutrophils, which are the first line of defense against infections. Although PVL can induce neutrophil death by...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoling, Chang, Wenjiao, Zhang, Cuiping, Zhou, Xin, Yu, Fangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329533/
https://www.ncbi.nlm.nih.gov/pubmed/22529963
http://dx.doi.org/10.1371/journal.pone.0034970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329533/
https://www.ncbi.nlm.nih.gov/pubmed/22529963
http://dx.doi.org/10.1371/journal.pone.0034970

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